Non-small cell lung cancer, adenocarcinoma

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Endpoint definition

FinnGen phenotype data
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Filter registries Death, Cancer

Cause of death: ICD-10 C34
Cause of death: ICD-9 162
Cause of death: ICD-8 162
Cancer registry: Topography ICD-O-3 C34
Cancer registry: Morphology ICD-O-3 8140
Cancer registry: Behaviour codes 3

Check pre-conditions None

Include endpoints None

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Check conditions

HLP_C3_NSCLC_ADENO

Apply sex-specific rule None

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Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 928 367 561
Unadjusted prevalence (%) 0.36 0.25 0.50
Mean age at first event (years) 68.23 67.31 68.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.46 41.23 [26.79, 63.47] 4.3e-64 421
15 years 0.26 42.05 [27.48, 64.35] 1.6e-66 417
5 years - - - -
1 year - - - -

Correlations

Index endpoint: C3_NSCLC_ADENO – Non-small cell lung cancer, adenocarcinoma
GWS hits: 1

Survival analyses between endpoints

Plot

before Non-small cell lung cancer, adenocarcinoma
after Non-small cell lung cancer, adenocarcinoma

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Drugs most likely to be purchased after Non-small cell lung cancer, adenocarcinoma