Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
CHOLELITH_BROAD
Extra metadata
First used in FinnGen datafreeze
DF3
Cholelithiasis, broad definition with cholecystitis
cholelithiasis: The presence of calculi in the gallbladder.
CHOLELITH_BROAD
Similar endpoints
↥List of similar endpoints to
Cholelithiasis, broad definition with cholecystitis
based on the number of shared cases.
Broader endpoints:
- Disorders of gallbladder, biliary tract and pancreas
- Gastrointestinal diseases
- Diseases of the digestive system
- Any ICDMAIN event in hilmo or causes of death
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 24101 | 16567 | 7534 |
| Unadjusted prevalence (%) | 9.27 | 11.27 | 6.66 |
| Mean age at first event (years) | 51.30 | 48.31 | 57.86 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.61 [1.44, 1.80] | 8.4e-17 | 3127 |
| 15 years | 0.01 | 1.84 [1.67, 2.02] | 3.8e-35 | 2402 |
| 5 years | 0.00 | 2.85 [2.57, 3.15] | 6.3e-90 | 994 |
| 1 year | 0.00 | 5.28 [4.49, 6.20] | 2.9e-91 | 349 |
Correlations
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Index endpoint: CHOLELITH_BROAD – Cholelithiasis, broad definition with cholecystitis
GWS hits: 43
Survival analyses between endpoints
↥Plot
before Cholelithiasis, broad definition with cholecystitis
after Cholelithiasis, broad definition with cholecystitis
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Table
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