Retinopathy of prematurity

retinopathy of prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H35.1
Hospital discharge: ICD-9 3622A
Hospital discharge: ICD-8 37704
Cause of death: ICD-10 H35.1
Cause of death: ICD-9 3622A
Cause of death: ICD-8 37704

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_RETINOPATPREMAT

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H35
Name in latin Retinopathia praematuritatis

Summary Statistics

Key figures

All Female Male
Number of individuals 60 35 25
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 36.81 41.24 30.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: H7_RETINOPATPREMAT – Retinopathy of prematurity
GWS hits:

Survival analyses between endpoints

Plot

before Retinopathy of prematurity
after Retinopathy of prematurity

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Drugs most likely to be purchased after Retinopathy of prematurity