Disorders of vitreous body and globe

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H43-H45
Cause of death: ICD-10 H43-H45

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of vitreous body and globe based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 8876 5559 3317
Unadjusted prevalence (%) 3.41 3.78 2.93
Mean age at first event (years) 61.23 60.84 61.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [1.12, 2.00] 6.6e-3 641
15 years 0.01 1.85 [1.47, 2.33] 1.7e-7 582
5 years 0.00 2.86 [2.34, 3.50] 6.4e-25 251
1 year 0.00 2.66 [1.90, 3.73] 1.5e-8 45

Correlations

Index endpoint: H7_VITREOUS – Disorders of vitreous body and globe
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of vitreous body and globe
after Disorders of vitreous body and globe

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Drugs most likely to be purchased after Disorders of vitreous body and globe