Drug phototoxic response

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L56.0#
Cause of death: ICD-10 L56.0#

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_DRUGPHOTOX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L56
Name in latin Reactio phototoxica medicamento provocata

Summary Statistics

Key figures

All Female Male
Number of individuals 15 10 -
Unadjusted prevalence (%) 0.01 0.01 -
Mean age at first event (years) 58.43 54.55 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: L12_DRUGPHOTOX – Drug phototoxic response
GWS hits:

Survival analyses between endpoints

Plot

before Drug phototoxic response
after Drug phototoxic response

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Drugs most likely to be purchased after Drug phototoxic response