Hidradenitis suppurativa

hidradenitis suppurativa: a common (though rarely diagnosed), chronic skin disease characterized by clusters of abscesses or subcutaneous boil-like "infections" (oftentimes free of actual bacteria) that most commonly affects apocrine sweat gland bearing areas, such as the underarms, under the breasts, inner thighs, groin and buttocks.The disease is not contagious. There are indications that it is hereditary among certain ethnic groups and autoimmune in nature. Onset is most common in the late teens and early 20's.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L73.2
Hospital discharge: ICD-9 7058C
Cause of death: ICD-10 L73.2
Cause of death: ICD-9 7058C

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_HIDRADENITISSUP

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L73
Name in latin Hidradenitis suppurativa

Summary Statistics

Key figures

All Female Male
Number of individuals 535 371 164
Unadjusted prevalence (%) 0.21 0.25 0.15
Mean age at first event (years) 41.49 39.65 45.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.23 [2.28, 17.04] 3.6e-4 25
15 years 0.05 7.38 [3.13, 17.44] 5.1e-6 20
5 years - - - -
1 year - - - -

Correlations

Index endpoint: L12_HIDRADENITISSUP – Hidradenitis suppurativa
GWS hits: 1

Survival analyses between endpoints

Plot

before Hidradenitis suppurativa
after Hidradenitis suppurativa

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Drugs most likely to be purchased after Hidradenitis suppurativa