Respiratory insufficiency

respiratory failure: The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIT:C26872]

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 J96.1
Cause of death: ICD-10 J96.1

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RESPIRATORYINSUFF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J96
Name in latin Insufficientia respiratoria chronica

Summary Statistics

Key figures

All Female Male
Number of individuals 1179 444 735
Unadjusted prevalence (%) 0.45 0.30 0.65
Mean age at first event (years) 68.08 66.19 69.22

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.33 27.47 [19.73, 38.24] 1.0e-85 596
15 years 0.17 27.68 [19.85, 38.60] 2.3e-85 593
5 years - - - -
1 year - - - -

Correlations

Index endpoint: RESPIRATORYINSUFF – Respiratory insufficiency
GWS hits: 0

Survival analyses between endpoints

Plot

before Respiratory insufficiency
after Respiratory insufficiency

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Drugs most likely to be purchased after Respiratory insufficiency