Viral infections characterized by skin and mucous membrane lesions

DOID EFO MESH SNOMED PheWeb

rubella: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis. [ url:http://en.wikipedia.org/wiki/Rubella ]

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 B00-B09

Hospital discharge: ICD-9 078[0-4]

Hospital discharge: ICD-8 079[0-1]

Hospital discharge: excluded ICD-9 0781C|0785|078[7-8]

Cause of death: ICD-10 B00-B09

Cause of death: ICD-9 078[0-4]

Cause of death: ICD-8 079[0-1]

Cause of death: excluded ICD-9 0781C|0785|078[7-8]

Check pre-conditions None

Include endpoints

AB1_HERPES_SIMPLEX

AB1_VARICELLA

AB1_ZOSTER

AB1_SMALLPOS

AB1_MONKEYPOS

AB1_MEASLES

AB1_RUBELLA

AB1_VIRAL_WARTS

AB1_VIRAL_SKIN_NOS

Check conditions None

Apply sex-specific rule None

AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Viral infections characterized by skin and mucous membrane lesions based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8456	4559	3897
Unadjusted prevalence (%)	3.25	3.10	3.45
Mean age at first event (years)	41.39	43.10	39.38

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.25 [1.71, 2.95]	5.4e-9	713
15 years	0.02	2.66 [2.08, 3.40]	8.2e-15	612
5 years	0.01	5.03 [4.12, 6.15]	5.6e-56	327
1 year	0.00	8.34 [6.43, 10.82]	1.2e-57	108

Correlations

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Index endpoint: AB1_VIRAL_SKIN_MUCOUS_MEMBRANE – Viral infections characterized by skin and mucous membrane lesions
GWS hits: 1

Survival analyses between endpoints

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Plot

before Viral infections characterized by skin and mucous membrane lesions
after Viral infections characterized by skin and mucous membrane lesions

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Table

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Drugs most likely to be purchased after Viral infections characterized by skin and mucous membrane lesions

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