Acute alcohol intoxication

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F10.0
Cause of death: ICD-10 F10.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector ALCOHOLACUTE10

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F10

Summary Statistics

Key figures

All Female Male
Number of individuals 3944 1366 2578
Unadjusted prevalence (%) 1.52 0.93 2.28
Mean age at first event (years) 47.60 41.68 50.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 17.24 [11.95, 24.88] 2.7e-52 823
15 years 0.12 19.96 [13.70, 29.07] 6.8e-55 798
5 years - - - -
1 year - - - -

Correlations

Index endpoint: ALCOHOLACUTE10 – Acute alcohol intoxication
GWS hits: 1

Survival analyses between endpoints

Plot

before Acute alcohol intoxication
after Acute alcohol intoxication

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Drugs most likely to be purchased after Acute alcohol intoxication