Alcoholic liver disease

Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K70
Hospital discharge: ICD-9 571[0-3]
Hospital discharge: ICD-8 5710
Cause of death: ICD-10 K70
Cause of death: ICD-9 571[0-3]
Cause of death: ICD-8 5710

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector ALCOLIVER

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K70-K77
Name in latin Morbus hepatis alcoholicus

Summary Statistics

Key figures

All Female Male
Number of individuals 1733 447 1286
Unadjusted prevalence (%) 0.67 0.30 1.14
Mean age at first event (years) 55.79 53.83 56.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: ALCOLIVER – Alcoholic liver disease
GWS hits: 1

Survival analyses between endpoints

Plot

before Alcoholic liver disease
after Alcoholic liver disease

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Drugs most likely to be purchased after Alcoholic liver disease