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Acute myeloid leukaemia

DOIDEFOMESHSNOMED PheWeb

acute myeloid leukemia: Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.

Endpoint definition

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FinnGen phenotype data
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Filter registries Death, Cancer

Cause of death: ICD-10 C92
Cause of death: ICD-9 204
Cause of death: ICD-8 204
Cancer registry: Topography ICD-O-3 C42|C77
Cancer registry: Morphology ICD-O-3 9861
Cancer registry: Behaviour codes 3

Check pre-conditions None

Include endpoints None

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Check conditions

HLP_C3_AML

Apply sex-specific rule None

diagram downward connector C3_AML

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 118 44 74
Unadjusted prevalence (%) 0.05 0.03 0.07
Mean age at first event (years) 64.35 59.19 67.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: C3_AML – Acute myeloid leukaemia
GWS hits: 0

Survival analyses between endpoints

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Plot

before Acute myeloid leukaemia
after Acute myeloid leukaemia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute myeloid leukaemia

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