Non-small cell lung cancer, adenocarcinoma

DOID EFO MESH SNOMED PheWeb

non-small cell lung carcinoma: A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy.

Endpoint definition

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FinnGen phenotype data

Filter registries Death, Cancer

Cause of death: ICD-10 C34

Cause of death: ICD-9 162

Cause of death: ICD-8 162

Cancer registry: Topography ICD-O-3 C34

Cancer registry: Morphology ICD-O-3 8140

Cancer registry: Behaviour codes 3

Check pre-conditions None

Include endpoints None

Check conditions

HLP_C3_NSCLC_ADENO

Apply sex-specific rule None

C3_NSCLC_ADENO

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Non-small cell lung cancer, adenocarcinoma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	928	367	561
Unadjusted prevalence (%)	0.36	0.25	0.50
Mean age at first event (years)	68.23	67.31	68.83

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.46	41.23 [26.79, 63.47]	4.3e-64	421
15 years	0.26	42.05 [27.48, 64.35]	1.6e-66	417
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: C3_NSCLC_ADENO – Non-small cell lung cancer, adenocarcinoma
GWS hits: 1

Survival analyses between endpoints

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Plot

before Non-small cell lung cancer, adenocarcinoma
after Non-small cell lung cancer, adenocarcinoma

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Table

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Drugs most likely to be purchased after Non-small cell lung cancer, adenocarcinoma

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