Melanoma in situ

melanoma: A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D03
Cause of death: ICD-10 D03

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector CD2_INSITU_MELANOMA

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D00-D09
Name in latin Melanoma in situ

Similar endpoints

List of similar endpoints to Melanoma in situ based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 490 253 237
Unadjusted prevalence (%) 0.19 0.17 0.21
Mean age at first event (years) 65.60 62.71 68.68


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.03 [0.46, 2.30] 9.5e-1 31
15 years 0.01 1.12 [0.51, 2.46] 7.7e-1 31
5 years 0.00 1.62 [0.72, 3.62] 2.4e-1 16
1 year - - - -


Index endpoint: CD2_INSITU_MELANOMA – Melanoma in situ
GWS hits: 0

Survival analyses between endpoints


before Melanoma in situ
after Melanoma in situ

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Drugs most likely to be purchased after Melanoma in situ