Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 D50-D89

Cause of death: ICD-10 D50-D89

Check pre-conditions None

Include endpoints

D3_NUTRIANAEMIA

D3_HAEMOLYTICANAEMIA

D3_APLASTICANDOTHANAEMIA

D3_COAGDEF_PURPUR_HAEMORRHAGIC

D3_BLOODOTHER

D3_IMMUNEMECHANISM

Check conditions None

Apply sex-specific rule None

D3_BLOOD

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	23852	13474	10378
Unadjusted prevalence (%)	9.17	9.17	9.18
Mean age at first event (years)	54.72	51.45	58.96

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.19 [3.60, 4.88]	1.5e-76	4435
15 years	0.03	5.01 [4.41, 5.70]	<1e-100	4087
5 years	0.01	9.51 [8.59, 10.53]	<1e-100	2721
1 year	0.00	19.62 [17.09, 22.52]	<1e-100	1240

Correlations

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Index endpoint: D3_BLOOD – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
GWS hits: 2

Survival analyses between endpoints

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Plot

before Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
after Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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Table

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Drugs most likely to be purchased after Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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