Adrenocortical insufficiency

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 E27.1, E27.2, E27.3#, E27.4
Hospital discharge: ICD-9 2554
Hospital discharge: ICD-8 2551
Cause of death: ICD-10 E27.1, E27.2, E27.3#, E27.4
Cause of death: ICD-9 2554
Cause of death: ICD-8 2551
KELA reimbursements: KELA codes 105

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_ADDISON

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 531 350 181
Unadjusted prevalence (%) 0.20 0.24 0.16
Mean age at first event (years) 48.48 47.82 49.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.45 [0.96, 6.25] 6.0e-2 61
15 years 0.03 3.71 [1.72, 7.98] 8.1e-4 57
5 years 0.01 7.07 [3.73, 13.41] 2.2e-9 36
1 year - - - -

Correlations

Index endpoint: E4_ADDISON – Adrenocortical insufficiency
GWS hits: 1

Survival analyses between endpoints

Plot

before Adrenocortical insufficiency
after Adrenocortical insufficiency

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Adrenocortical insufficiency