Ovarian dysfunction: estrogen excess

hyperestrogenism: ['Abnormally high level of estrogen. [ NICHD NCI ]']

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E28.0#

Hospital discharge: ICD-9 2560

Hospital discharge: ICD-8 2560

Cause of death: ICD-10 E28.0#

Cause of death: ICD-9 2560

Cause of death: ICD-8 2560

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule

Sex only females

E4_ODESTRO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E28

Name in latin Hypersecretio oestrogenorum

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List of similar endpoints to Ovarian dysfunction: estrogen excess based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

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Index endpoint: E4_ODESTRO – Ovarian dysfunction: estrogen excess
GWS hits:

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before Ovarian dysfunction: estrogen excess
after Ovarian dysfunction: estrogen excess

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