Thyrotoxicosis with toxic multinodular goitre

Toxic Nodular Goiter: Nodular enlargement of the thyroid gland associated with hyperthyroidism.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E05.2
Hospital discharge: ICD-9 2422
Hospital discharge: ICD-8 2421
Cause of death: ICD-10 E05.2
Cause of death: ICD-9 2422
Cause of death: ICD-8 2421

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_THYTOXGOITMULT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E05
Name in latin Thyreotoxicosis cum struma multinodulari

Summary Statistics

Key figures

All Female Male
Number of individuals 951 788 163
Unadjusted prevalence (%) 0.37 0.54 0.14
Mean age at first event (years) 56.26 55.39 60.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.15 [1.36, 3.40] 1.0e-3 99
15 years 0.01 2.17 [1.38, 3.41] 7.6e-4 74
5 years 0.00 3.60 [2.33, 5.57] 7.5e-9 33
1 year - - - -

Correlations

Index endpoint: E4_THYTOXGOITMULT – Thyrotoxicosis with toxic multinodular goitre
GWS hits: 7

Survival analyses between endpoints

Plot

before Thyrotoxicosis with toxic multinodular goitre
after Thyrotoxicosis with toxic multinodular goitre

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Drugs most likely to be purchased after Thyrotoxicosis with toxic multinodular goitre