Endpoint definition
↥Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
Extra metadata
Toxic Nodular Goiter: Nodular enlargement of the thyroid gland associated with hyperthyroidism.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
Extra metadata
List of similar endpoints to
		
			Thyrotoxicosis with toxic multinodular goitre
	based on the number of shared cases.
		
		Broader endpoints:
	
		
		Narrower endpoints:
	
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 951 | 788 | 163 | 
| Unadjusted prevalence (%) | 0.37 | 0.54 | 0.14 | 
| Mean age at first event (years) | 56.26 | 55.39 | 60.51 | 
| Follow-up | Absolute risk | HR [95% CI] | p | N | 
|---|---|---|---|---|
| 1998–2019 | 0.03 | 2.15 [1.36, 3.40] | 1.0e-3 | 99 | 
| 15 years | 0.01 | 2.17 [1.38, 3.41] | 7.6e-4 | 74 | 
| 5 years | 0.00 | 3.60 [2.33, 5.57] | 7.5e-9 | 33 | 
| 1 year | - | - | - | - | 
	Index endpoint: E4_THYTOXGOITMULT – Thyrotoxicosis with toxic multinodular goitre
	GWS hits: 7
						 before Thyrotoxicosis with toxic multinodular goitre
						
						 after Thyrotoxicosis with toxic multinodular goitre
					
						
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