Thyrotoxicosis with toxic single thyroid nodule

Hyperthyroidism: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E05.1
Hospital discharge: ICD-9 2421
Cause of death: ICD-10 E05.1
Cause of death: ICD-9 2421

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_THYTOXNOD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E05
Name in latin Thyreotoxicosis cum struma uninodulari

Summary Statistics

Key figures

All Female Male
Number of individuals 136 115 21
Unadjusted prevalence (%) 0.05 0.08 0.02
Mean age at first event (years) 51.36 49.05 64.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: E4_THYTOXNOD – Thyrotoxicosis with toxic single thyroid nodule
GWS hits: 1

Survival analyses between endpoints

Plot

before Thyrotoxicosis with toxic single thyroid nodule
after Thyrotoxicosis with toxic single thyroid nodule

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Drugs most likely to be purchased after Thyrotoxicosis with toxic single thyroid nodule