Vitamin deficiency

ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E50, E51, E52, E52+F02.89, E53, E54, E55, E56
Cause of death: ICD-10 E50, E51, E52, E52+F02.89, E53, E54, E55, E56

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_VIT_DEF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 780 467 313
Unadjusted prevalence (%) 0.30 0.32 0.28
Mean age at first event (years) 52.24 49.89 55.73


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.42 [3.19, 9.20] 4.0e-10 126
15 years 0.04 6.18 [3.81, 10.02] 1.7e-13 118
5 years - - - -
1 year - - - -


Index endpoint: E4_VIT_DEF – Vitamin deficiency
GWS hits: 0

Survival analyses between endpoints


before Vitamin deficiency
after Vitamin deficiency

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Drugs most likely to be purchased after Vitamin deficiency