Generalized anxiety disorder

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F41.1
Hospital discharge: ICD-9 3000C
Cause of death: ICD-10 F41.1
Cause of death: ICD-9 3000C

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_GAD

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Perturbatio anxifera generalisata

Summary Statistics

Key figures

All Female Male
Number of individuals 2592 1780 812
Unadjusted prevalence (%) 1.00 1.21 0.72
Mean age at first event (years) 40.31 40.25 40.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.33 [1.82, 6.10] 9.4e-5 77
15 years 0.03 3.96 [2.39, 6.58] 1.0e-7 65
5 years 0.01 7.01 [4.39, 11.17] 2.9e-16 31
1 year 0.00 13.52 [6.86, 26.63] 5.1e-14 11

Correlations

Index endpoint: F5_GAD – Generalized anxiety disorder
GWS hits: 1

Survival analyses between endpoints

Plot

before Generalized anxiety disorder
after Generalized anxiety disorder

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Drugs most likely to be purchased after Generalized anxiety disorder