Obsessive-compulsive disorder

obsessive-compulsive disorder: A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F42
Hospital discharge: ICD-9 3003
Hospital discharge: ICD-8 3003
Cause of death: ICD-10 F42
Cause of death: ICD-9 3003
Cause of death: ICD-8 3003

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector F5_OCD

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F40-F48
Name in latin Perturbatio obsessivo-compulsiva

Summary Statistics

Key figures

All Female Male
Number of individuals 1232 752 480
Unadjusted prevalence (%) 0.47 0.51 0.42
Mean age at first event (years) 32.54 32.28 32.94

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.54 [1.82, 6.87] 1.9e-4 42
15 years 0.03 4.44 [2.40, 8.21] 2.0e-6 33
5 years 0.01 6.00 [2.76, 13.05] 6.2e-6 11
1 year - - - -

Correlations

Index endpoint: F5_OCD – Obsessive-compulsive disorder
GWS hits: 0

Survival analyses between endpoints

Plot

before Obsessive-compulsive disorder
after Obsessive-compulsive disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obsessive-compulsive disorder