Congenital and developmental myasthenia

Myasthenia gravis: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G70.20, G70.21, G70.28
Cause of death: ICD-10 G70.20, G70.21, G70.28

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_CONDEVMYA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 14 8 6
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 56.51 47.93 67.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: G6_CONDEVMYA – Congenital and developmental myasthenia
GWS hits:

Survival analyses between endpoints

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Plot

before Congenital and developmental myasthenia
after Congenital and developmental myasthenia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Congenital and developmental myasthenia

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