Other and unspecified degenerative diseases of nervous system

Lewy body dementia: A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and loss of cholinergic and dopaminergic neurons. The signs and symptoms overlap with Alzheimer and Parkinson disease.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G31.8, G31.9, G32*
Hospital discharge: ICD-9 331[8-9]
Hospital discharge: ICD-8 32303
Cause of death: ICD-10 G31.8, G31.9, G32*
Cause of death: ICD-9 331[8-9]
Cause of death: ICD-8 32303

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_DEGENOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 296 121 175
Unadjusted prevalence (%) 0.11 0.08 0.15
Mean age at first event (years) 65.17 62.07 67.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: G6_DEGENOTH – Other and unspecified degenerative diseases of nervous system
GWS hits: 0

Survival analyses between endpoints

Plot

before Other and unspecified degenerative diseases of nervous system
after Other and unspecified degenerative diseases of nervous system

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Drugs most likely to be purchased after Other and unspecified degenerative diseases of nervous system