Migraine

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G43
Hospital discharge: ICD-9 346
Hospital discharge: ICD-8 346
Hospital discharge: excluded ICD-8 34601
Cause of death: ICD-10 G43
Cause of death: ICD-9 346
Cause of death: ICD-8 346
Cause of death: excluded ICD-8 34601

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_MIGRAINE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Hemicrania

Summary Statistics

Key figures

All Female Male
Number of individuals 10536 8647 1889
Unadjusted prevalence (%) 4.05 5.88 1.67
Mean age at first event (years) 40.27 40.15 40.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.38 [0.97, 1.96] 7.1e-2 240
15 years 0.01 1.49 [1.11, 2.00] 7.3e-3 170
5 years 0.00 1.45 [1.00, 2.11] 5.1e-2 41
1 year 0.00 1.99 [1.03, 3.86] 4.2e-2 10

Correlations

Index endpoint: G6_MIGRAINE – Migraine
GWS hits: 4

Survival analyses between endpoints

Plot

before Migraine
after Migraine

loading spinner Loading survival analyses plot