Migraine

migraine disorder: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G43
Hospital discharge: ICD-9 346
Hospital discharge: ICD-8 346
Hospital discharge: excluded ICD-8 34601
Cause of death: ICD-10 G43
Cause of death: ICD-9 346
Cause of death: ICD-8 346
Cause of death: excluded ICD-8 34601

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_MIGRAINE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Hemicrania

Summary Statistics

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Key figures

All Female Male
Number of individuals 10536 8647 1889
Unadjusted prevalence (%) 4.05 5.88 1.67
Mean age at first event (years) 40.27 40.15 40.84

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.38 [0.97, 1.96] 7.1e-2 240
15 years 0.01 1.49 [1.11, 2.00] 7.3e-3 170
5 years 0.00 1.45 [1.00, 2.11] 5.1e-2 41
1 year 0.00 1.99 [1.03, 3.86] 4.2e-2 10

Correlations

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Index endpoint: G6_MIGRAINE – Migraine
GWS hits: 4

Survival analyses between endpoints

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Plot

before Migraine
after Migraine

loading spinner Loading survival analyses plot