Myasthenia gravis

Myasthenia gravis: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 G70.0#
Hospital discharge: ICD-9 3580
Hospital discharge: ICD-8 7330
Cause of death: ICD-10 G70.0#
Cause of death: ICD-9 3580
Cause of death: ICD-8 7330
KELA reimbursements: KELA codes 108

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_MYASTHENIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G70

Summary Statistics

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Key figures

All Female Male
Number of individuals 283 156 127
Unadjusted prevalence (%) 0.11 0.11 0.11
Mean age at first event (years) 51.60 45.63 58.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.76 [1.38, 5.51] 3.9e-3 28
15 years 0.02 3.10 [1.63, 5.89] 5.4e-4 21
5 years 0.01 6.77 [3.02, 15.16] 3.4e-6 12
1 year - - - -

Correlations

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Index endpoint: G6_MYASTHENIA – Myasthenia gravis
GWS hits: 0

Survival analyses between endpoints

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Plot

before Myasthenia gravis
after Myasthenia gravis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Myasthenia gravis

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