Myasthenia gravis

Myasthenia gravis: Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 G70.0#
Hospital discharge: ICD-9 3580
Hospital discharge: ICD-8 7330
Cause of death: ICD-10 G70.0#
Cause of death: ICD-9 3580
Cause of death: ICD-8 7330
KELA reimbursements: KELA codes 108

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_MYASTHENIA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G70

Summary Statistics

Key figures

All Female Male
Number of individuals 283 156 127
Unadjusted prevalence (%) 0.11 0.11 0.11
Mean age at first event (years) 51.60 45.63 58.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.76 [1.38, 5.51] 3.9e-3 28
15 years 0.02 3.10 [1.63, 5.89] 5.4e-4 21
5 years 0.01 6.77 [3.02, 15.16] 3.4e-6 12
1 year - - - -

Correlations

Index endpoint: G6_MYASTHENIA – Myasthenia gravis
GWS hits: 0

Survival analyses between endpoints

Plot

before Myasthenia gravis
after Myasthenia gravis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Myasthenia gravis