Other inherited muscular atrophy

amyotrophic lateral sclerosis: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G12.1
Hospital discharge: ICD-9 3351A
Cause of death: ICD-10 G12.1
Cause of death: ICD-9 3351A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_OTHINMUSC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G12
Name in latin Alia atrophia musculorum spinalis congenita

Summary Statistics

Key figures

All Female Male
Number of individuals 24 9 15
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 55.50 54.76 55.95

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: G6_OTHINMUSC – Other inherited muscular atrophy
GWS hits:

Survival analyses between endpoints

Plot

before Other inherited muscular atrophy
after Other inherited muscular atrophy

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Drugs most likely to be purchased after Other inherited muscular atrophy