Other and unspecified spinal muscular atrophies

DOID EFO MESH SNOMED PheWeb

spinal muscular atrophy: Spinal muscular atrophy is a disorder of spinal motor neurons characterized clinically by the development of muscle weakness and atrophy.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G12.8, G12.9, G13*

Hospital discharge: ICD-9 335

Hospital discharge: ICD-8 34829|3489

Hospital discharge: excluded ICD-9 3350A|3351A|3352A

Cause of death: ICD-10 G12.8, G12.9, G13*

Cause of death: ICD-9 335

Cause of death: ICD-8 34829|3489

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

G6_SPINAMUSCOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified spinal muscular atrophies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	135	48	87
Unadjusted prevalence (%)	0.05	0.03	0.08
Mean age at first event (years)	55.60	48.20	59.67

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: G6_SPINAMUSCOTH – Other and unspecified spinal muscular atrophies
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other and unspecified spinal muscular atrophies
after Other and unspecified spinal muscular atrophies

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Table

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Drugs most likely to be purchased after Other and unspecified spinal muscular atrophies

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