Trigeminal neuralgia

trigeminal neuralgia: Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain lasts a few seconds to a few minutes, and usually on only one side of the face. It can also cause muscle spasms in the face the same time as the pain. The pain may result from a blood vessel pressing against the trigeminal nerve (the nerve that carries pain, feeling, and other sensations from the brain to the skin of theface), as a complication of multiple sclerosis, or due to compression of the nerve by a tumor or cyst. In some cases, the cause is unknown. Treatment options include medicines, surgery, and complementary approaches.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 G50.0
Hospital discharge: ICD-9 3501
Hospital discharge: ICD-8 35199
Cause of death: ICD-10 G50.0
Cause of death: ICD-9 3501
Cause of death: ICD-8 35199
KELA reimbursements: KELA codes 119

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector G6_TRINEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G50
Name in latin Neuralgia trigeminalis

Summary Statistics

Key figures

All Female Male
Number of individuals 957 667 290
Unadjusted prevalence (%) 0.37 0.45 0.26
Mean age at first event (years) 54.23 53.18 56.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.75 [0.34, 1.67] 4.9e-1 75
15 years 0.01 0.96 [0.48, 1.93] 9.2e-1 59
5 years 0.00 1.47 [0.74, 2.90] 2.7e-1 19
1 year - - - -

Correlations

Index endpoint: G6_TRINEU – Trigeminal neuralgia
GWS hits: 0

Survival analyses between endpoints

Plot

before Trigeminal neuralgia
after Trigeminal neuralgia

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Drugs most likely to be purchased after Trigeminal neuralgia