Use of antiglaucoma preparations and miotics

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC S01EA
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_GLAUCOMAMEDICATION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1585 894 691
Unadjusted prevalence (%) 0.61 0.61 0.61
Mean age at first event (years) 65.12 64.78 65.56

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.35, 2.57] 1.7e-4 321
15 years 0.01 1.97 [1.50, 2.59] 9.8e-7 283
5 years 0.00 2.26 [1.71, 3.00] 1.3e-8 97
1 year 0.00 1.23 [0.63, 2.37] 5.5e-1 10

Correlations

Index endpoint: H7_GLAUCOMAMEDICATION – Use of antiglaucoma preparations and miotics
GWS hits: 2

Survival analyses between endpoints

Plot

before Use of antiglaucoma preparations and miotics
after Use of antiglaucoma preparations and miotics

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Use of antiglaucoma preparations and miotics