Primary open-angle glaucoma, strict

open-angle glaucoma: Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H40.1
Hospital discharge: ICD-9 3651[A|C|E|X]
Hospital discharge: ICD-8 37510
Hospital discharge: excluded ICD-10 H40.10, H40.12
Cause of death: ICD-10 H40.1
Cause of death: ICD-9 3651[A|C|E|X]
Cause of death: ICD-8 37510
Cause of death: excluded ICD-10 H40.10, H40.12

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_GLAUCOMA_POAG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H40
Name in latin Glaucoma simplex primarium

Summary Statistics

Key figures

All Female Male
Number of individuals 4163 2318 1845
Unadjusted prevalence (%) 1.60 1.58 1.63
Mean age at first event (years) 66.36 66.15 66.62


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.88 [1.47, 2.40] 4.4e-7 669
15 years 0.01 1.95 [1.56, 2.44] 4.2e-9 570
5 years 0.00 2.06 [1.69, 2.53] 2.7e-12 208
1 year 0.00 2.34 [1.67, 3.28] 8.9e-7 45


Index endpoint: H7_GLAUCOMA_POAG – Primary open-angle glaucoma, strict
GWS hits: 15

Survival analyses between endpoints


before Primary open-angle glaucoma, strict
after Primary open-angle glaucoma, strict

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary open-angle glaucoma, strict