Hereditary corneal dystrophies

DOID MESH PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H18.5

Hospital discharge: ICD-9 3715

Hospital discharge: ICD-8 37102

Cause of death: ICD-10 H18.5

Cause of death: ICD-9 3715

Cause of death: ICD-8 37102

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

H7_KERATOCONUS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H18

Name in latin Dystrophia corneae hereditaria

Similar endpoints

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List of similar endpoints to Hereditary corneal dystrophies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

408

272

136

Unadjusted prevalence (%)

0.16

0.19

0.12

Mean age at first event (years)

60.65

60.52

60.91

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Methods page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.93 [0.34, 2.53]	8.9e-1	24
15 years	0.01	1.27 [0.44, 3.65]	6.6e-1	23
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: H7_KERATOCONUS – Hereditary corneal dystrophies
GWS hits: 3

Survival analyses between endpoints

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Plot

before Hereditary corneal dystrophies
after Hereditary corneal dystrophies

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hereditary corneal dystrophies

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