Ototoxic hearing loss

nonsyndromic deafness: An auditory system disease that is associated with permanent hearing loss caused by damage to structures in the inner ear and/or the middle ear, which is not associated with other signs and symptoms.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H91.0#
Cause of death: ICD-10 H91.0#

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H8_HL_OTOTOX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Hypacusis ototoxica

Summary Statistics

Key figures

All Female Male
Number of individuals 29 16 13
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 58.17 59.06 57.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: H8_HL_OTOTOX – Ototoxic hearing loss
GWS hits:

Survival analyses between endpoints

Plot

before Ototoxic hearing loss
after Ototoxic hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ototoxic hearing loss