otosclerosis: Formation of spongy bone in the labyrinth capsule which can progress toward the stapes (stapedial fixation) or anteriorly toward the cochlea leading to conductive, sensorineural, or mixed hearing loss. Several genes are associated with familial otosclerosis with varied clinical signs.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
H8_OTOSCLE
Extra metadata
List of similar endpoints to
Otosclerosis
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1563 | 1002 | 561 |
| Unadjusted prevalence (%) | 0.60 | 0.68 | 0.50 |
| Mean age at first event (years) | 45.74 | 44.67 | 47.66 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.03 [0.68, 1.57] | 8.8e-1 | 114 |
| 15 years | 0.01 | 1.03 [0.67, 1.56] | 9.0e-1 | 69 |
| 5 years | 0.00 | 1.05 [0.60, 1.85] | 8.7e-1 | 15 |
| 1 year | - | - | - | - |
Index endpoint: H8_OTOSCLE – Otosclerosis
GWS hits: 13
before Otosclerosis
after Otosclerosis
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