Peripheral artery disease

DOID EFO MESH SNOMED PheWeb

peripheral arterial disease: A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E10.5, E10.5+I79.2, E11.5, E11.5+I79.2, E12.5, E13.5, E14.5, I70.2, I73.9

Hospital discharge: ICD-9 4402|4439

Hospital discharge: ICD-8 25006|4402|4439

Cause of death: ICD-10 E10.5, E10.5+I79.2, E11.5, E11.5+I79.2, E12.5, E13.5, E14.5, I70.2, I73.9

Cause of death: ICD-9 4402|4439

Cause of death: ICD-8 25006|4402|4439

Check pre-conditions None

Include endpoints

I9_PERIPH

Check conditions None

Apply sex-specific rule None

I9_PAD

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Peripheral artery disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	9008	2976	6032
Unadjusted prevalence (%)	3.46	2.03	5.33
Mean age at first event (years)	65.36	65.72	65.18

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	5.53 [4.83, 6.33]	<1e-100	3134
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: I9_PAD – Peripheral artery disease
GWS hits: 1

Survival analyses between endpoints

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Plot

before Peripheral artery disease
after Peripheral artery disease

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Table

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Drugs most likely to be purchased after Peripheral artery disease

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