All influenza (not pneumonia)

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Hospital discharge: excluded ICD-10 J10.0, J11.0
Hospital discharge: excluded ICD-9 4870
Hospital discharge: excluded ICD-8 471
Cause of death: ICD-10 J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]
Cause of death: excluded ICD-10 4870
Cause of death: excluded ICD-9 471

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector INFLUENZA

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3225 1310 1915
Unadjusted prevalence (%) 1.24 0.89 1.69
Mean age at first event (years) 43.57 49.39 39.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.87 [0.99, 3.54] 5.5e-2 329
15 years 0.02 2.80 [1.66, 4.72] 1.1e-4 293
5 years 0.01 6.29 [4.45, 8.89] 2.3e-25 204
1 year - - - -

Correlations

Index endpoint: INFLUENZA – All influenza (not pneumonia)
GWS hits: 0

Survival analyses between endpoints

Plot

before All influenza (not pneumonia)
after All influenza (not pneumonia)

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Drugs most likely to be purchased after All influenza (not pneumonia)