celiac disease: An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
K11_COELIAC
Extra metadata
List of similar endpoints to
Coeliac disease
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2367 | 1585 | 782 |
| Unadjusted prevalence (%) | 0.91 | 1.08 | 0.69 |
| Mean age at first event (years) | 46.12 | 44.48 | 49.45 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.03 | 1.99 [1.28, 3.09] | 2.3e-3 | 140 |
| 15 years | 0.02 | 2.35 [1.50, 3.68] | 1.9e-4 | 123 |
| 5 years | 0.00 | 4.23 [2.80, 6.38] | 7.1e-12 | 54 |
| 1 year | 0.00 | 8.69 [5.12, 14.75] | 1.1e-15 | 21 |
Index endpoint: K11_COELIAC – Coeliac disease
GWS hits: 16
before Coeliac disease
after Coeliac disease
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