Diaphragmatic hernia

congenital diaphragmatic hernia: Congenital diaphragmatic hernia (CDH) is a posterolateral defect of the diaphragm that allows passage of abdominal viscera into the thorax, leading to respiratory insufficiency and persistent pulmonary hypertension with high mortality.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K44
Hospital discharge: ICD-9 5513|5523|5533
Hospital discharge: ICD-8 5513
Cause of death: ICD-10 K44
Cause of death: ICD-9 5513|5523|5533
Cause of death: ICD-8 5513

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_DIAHER

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K40-K46
Name in latin Hernia diaphragmatica

Summary Statistics

Key figures

All Female Male
Number of individuals 7023 4193 2830
Unadjusted prevalence (%) 2.70 2.85 2.50
Mean age at first event (years) 59.41 59.22 59.69


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.04 [1.34, 3.10] 9.6e-4 740
15 years 0.02 2.59 [1.86, 3.59] 1.3e-8 668
5 years 0.01 4.66 [3.66, 5.94] 1.2e-35 340
1 year 0.00 6.62 [4.94, 8.87] 8.5e-37 95


Index endpoint: K11_DIAHER – Diaphragmatic hernia
GWS hits: 6

Survival analyses between endpoints


before Diaphragmatic hernia
after Diaphragmatic hernia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diaphragmatic hernia