Fissure and fistula of anal and rectal regions

anus disease: A non-neoplastic or neoplastic disorder that affects the anal canal or anal margin. Representative examples of non-neoplastic disorders include hemorrhoids and anal ulcer. Representative examples of neoplastic disorders include carcinoma, lymphoma, and melanoma. [database_cross_reference: NCIT:C26695]

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K60
Hospital discharge: ICD-9 565
Hospital discharge: ICD-8 565
Cause of death: ICD-10 K60
Cause of death: ICD-9 565
Cause of death: ICD-8 565

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_FISSANAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Fissura/fistula regionis analis/rectalis

Summary Statistics

Key figures

All Female Male
Number of individuals 5499 2831 2668
Unadjusted prevalence (%) 2.11 1.93 2.36
Mean age at first event (years) 44.17 42.93 45.47

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.96 [0.73, 1.26] 7.7e-1 418
15 years 0.01 1.06 [0.84, 1.36] 6.1e-1 272
5 years 0.00 1.51 [1.14, 2.00] 4.2e-3 78
1 year 0.00 2.01 [1.21, 3.32] 6.6e-3 18

Correlations

Index endpoint: K11_FISSANAL – Fissure and fistula of anal and rectal regions
GWS hits: 1

Survival analyses between endpoints

Plot

before Fissure and fistula of anal and rectal regions
after Fissure and fistula of anal and rectal regions

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Fissure and fistula of anal and rectal regions