Irritable bowel syndrome

DOID EFO MESH SNOMED PheWeb

irritable bowel syndrome: Gastrointestinal symptoms characterized by chronic abdominal pain and altered bowel habits in the absence of any organic cause.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K58

Hospital discharge: ICD-9 5641

Hospital discharge: ICD-8 56419

Cause of death: ICD-10 K58

Cause of death: ICD-9 5641

Cause of death: ICD-8 56419

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

K11_IBS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K55-K63

Name in latin Syndroma intestini irritabilis

Similar endpoints

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List of similar endpoints to Irritable bowel syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5628	4151	1477
Unadjusted prevalence (%)	2.16	2.82	1.31
Mean age at first event (years)	48.91	48.36	50.46

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.11 [0.78, 1.59]	5.6e-1	301
15 years	0.01	1.26 [0.90, 1.75]	1.7e-1	237
5 years	0.00	1.87 [1.36, 2.56]	1.0e-4	87
1 year	0.00	3.10 [1.95, 4.91]	1.6e-6	25

Correlations

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Index endpoint: K11_IBS – Irritable bowel syndrome
GWS hits: 1

Survival analyses between endpoints

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Plot

before Irritable bowel syndrome
after Irritable bowel syndrome

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Table

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Drugs most likely to be purchased after Irritable bowel syndrome

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