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Any mental disorder

DOIDEFOMESHSNOMED PheWeb

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]
Hospital discharge: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310
Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]
Cause of death: ICD-9  29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A 
Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 62288 35586 26702
Unadjusted prevalence (%) 23.95 24.22 23.61
Mean age at first event (years) 41.80 40.60 43.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.93 [4.48, 5.44] <1e-100 8468
15 years 0.03 6.04 [5.57, 6.54] <1e-100 7323
5 years 0.01 11.02 [10.20, 11.90] <1e-100 4432
1 year 0.00 21.41 [18.87, 24.28] <1e-100 1952

Correlations

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Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder
GWS hits: 9

Survival analyses between endpoints

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Plot

before Any mental disorder
after Any mental disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Any mental disorder

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