Substance abuse

No definition available.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F10-F19
Hospital discharge: ICD-9 29[1-2]|30[3-5]
Hospital discharge: ICD-8 291|30[3-4]
Hospital discharge: excluded ICD-10 F10.0
Hospital discharge: excluded ICD-9 3050A
Cause of death: ICD-10 F10-F19
Cause of death: ICD-9 29[1-2]|30[3-5]
Cause of death: ICD-8 291|30[3-4]

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector KRA_PSY_SUBSTANCE

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 15459 5451 10008
Unadjusted prevalence (%) 5.95 3.71 8.85
Mean age at first event (years) 43.34 40.69 44.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.38 [5.27, 7.71] 1.4e-81 2629
15 years 0.04 7.86 [6.79, 9.09] <1e-100 2199
5 years 0.01 14.75 [13.07, 16.66] <1e-100 1153
1 year - - - -

Correlations

Index endpoint: KRA_PSY_SUBSTANCE – Substance abuse
GWS hits: 3

Survival analyses between endpoints

Plot

before Substance abuse
after Substance abuse

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