Atrophic disorders of skin

skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L90
Cause of death: ICD-10 L90

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_ATROPHICSKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Morbositates atrophicae cutis

Similar endpoints

List of similar endpoints to Atrophic disorders of skin based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 2035 1656 379
Unadjusted prevalence (%) 0.78 1.13 0.34
Mean age at first event (years) 53.33 54.62 47.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.82 [1.92, 4.16] 1.5e-7 83
15 years 0.02 3.04 [2.10, 4.39] 3.0e-9 67
5 years 0.00 3.11 [1.88, 5.15] 9.9e-6 26
1 year - - - -

Correlations

Index endpoint: L12_ATROPHICSKIN – Atrophic disorders of skin
GWS hits: 0

Survival analyses between endpoints

Plot

before Atrophic disorders of skin
after Atrophic disorders of skin

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Drugs most likely to be purchased after Atrophic disorders of skin