Drug phototoxic response

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L56.0#
Cause of death: ICD-10 L56.0#

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_DRUGPHOTOX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L56
Name in latin Reactio phototoxica medicamento provocata

Summary Statistics

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Key figures

All Female Male
Number of individuals 15 10 -
Unadjusted prevalence (%) 0.01 0.01 -
Mean age at first event (years) 58.43 54.55 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: L12_DRUGPHOTOX – Drug phototoxic response
GWS hits:

Survival analyses between endpoints

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Plot

before Drug phototoxic response
after Drug phototoxic response

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Drugs most likely to be purchased after Drug phototoxic response

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