Hypertrophic scar

osteoarthritis: A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L91.0
Hospital discharge: ICD-9 7014B
Hospital discharge: ICD-8 70130
Cause of death: ICD-10 L91.0
Cause of death: ICD-9 7014B
Cause of death: ICD-8 70130

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_HYPETROPHICSCAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L91
Name in latin Cicatrix cheloides

Summary Statistics

Key figures

All Female Male
Number of individuals 936 666 270
Unadjusted prevalence (%) 0.36 0.45 0.24
Mean age at first event (years) 40.19 38.81 43.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.86 [1.48, 5.53] 1.7e-3 38
15 years 0.02 3.11 [1.63, 5.92] 5.5e-4 28
5 years 0.00 4.08 [1.99, 8.35] 1.2e-4 10
1 year - - - -

Correlations

Index endpoint: L12_HYPETROPHICSCAR – Hypertrophic scar
GWS hits: 4

Survival analyses between endpoints

Plot

before Hypertrophic scar
after Hypertrophic scar

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertrophic scar