Linear scleroderma

scleroderma: Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc) (see these terms).

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L94.1
Cause of death: ICD-10 L94.1

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_LINEARSCLERODERMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L94
Name in latin Scleroderma lineare

Summary Statistics

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Key figures

All Female Male
Number of individuals 19 12 7
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 40.14 37.58 44.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: L12_LINEARSCLERODERMA – Linear scleroderma
GWS hits:

Survival analyses between endpoints

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Plot

before Linear scleroderma
after Linear scleroderma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Linear scleroderma

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