Linear scleroderma

scleroderma: Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc) (see these terms).

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L94.1
Cause of death: ICD-10 L94.1

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_LINEARSCLERODERMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L94
Name in latin Scleroderma lineare

Summary Statistics

Key figures

All Female Male
Number of individuals 19 12 7
Unadjusted prevalence (%) 0.01 0.01 0.01
Mean age at first event (years) 40.14 37.58 44.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: L12_LINEARSCLERODERMA – Linear scleroderma
GWS hits:

Survival analyses between endpoints

Plot

before Linear scleroderma
after Linear scleroderma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Linear scleroderma