Other specified/unspecified systemic involvement of connective tissue

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M35.8, M35.9
Hospital discharge: ICD-9 710[8-9]
Hospital discharge: ICD-8 7349[1-9]
Cause of death: ICD-10 M35.8, M35.9
Cause of death: ICD-9 710[8-9]
Cause of death: ICD-8 7349[1-9]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_CONNECTNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1039 828 211
Unadjusted prevalence (%) 0.40 0.56 0.19
Mean age at first event (years) 48.89 47.73 53.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.53 [3.33, 9.19] 4.1e-11 92
15 years 0.04 5.87 [3.80, 9.06] 1.3e-15 75
5 years 0.01 7.07 [4.29, 11.63] 1.5e-14 33
1 year - - - -

Correlations

Index endpoint: M13_CONNECTNAS – Other specified/unspecified systemic involvement of connective tissue
GWS hits: 1

Survival analyses between endpoints

Plot

before Other specified/unspecified systemic involvement of connective tissue
after Other specified/unspecified systemic involvement of connective tissue

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Drugs most likely to be purchased after Other specified/unspecified systemic involvement of connective tissue