Other specified/unspecified systemic involvement of connective tissue

connective tissue disease: A disorder characterized by abnormalities in one or more of the elements of the connective tissues, typically associated with genetic defects.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M35.8, M35.9
Hospital discharge: ICD-9 710[8-9]
Hospital discharge: ICD-8 7349[1-9]
Cause of death: ICD-10 M35.8, M35.9
Cause of death: ICD-9 710[8-9]
Cause of death: ICD-8 7349[1-9]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_CONNECTNAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1039 828 211
Unadjusted prevalence (%) 0.40 0.56 0.19
Mean age at first event (years) 48.89 47.73 53.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.53 [3.33, 9.19] 4.1e-11 92
15 years 0.04 5.87 [3.80, 9.06] 1.3e-15 75
5 years 0.01 7.07 [4.29, 11.63] 1.5e-14 33
1 year - - - -

Correlations

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Index endpoint: M13_CONNECTNAS – Other specified/unspecified systemic involvement of connective tissue
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other specified/unspecified systemic involvement of connective tissue
after Other specified/unspecified systemic involvement of connective tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other specified/unspecified systemic involvement of connective tissue

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