Giant cell arteritis

temporal arteritis: Giant cell arteritis (GCA) is a large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M31.5, M31.6
Hospital discharge: ICD-9 4465
Cause of death: ICD-10 M31.5, M31.6
Cause of death: ICD-9 4465

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_GIANTCELL

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 584 371 213
Unadjusted prevalence (%) 0.22 0.25 0.19
Mean age at first event (years) 67.62 67.27 68.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.94 [1.08, 8.04] 3.5e-2 88
15 years 0.03 3.80 [1.84, 7.88] 3.2e-4 84
5 years - - - -
1 year - - - -

Correlations

Index endpoint: M13_GIANTCELL – Giant cell arteritis
GWS hits: 0

Survival analyses between endpoints

Plot

before Giant cell arteritis
after Giant cell arteritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Giant cell arteritis