Wegener granulomatosis

Granulomatosis with Polyangiitis: A small-vessel necrotizing vasculitis characterised by the association of inflammation of the vessel wall and peri- and extravascular granulomatosis.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M31.3
Hospital discharge: ICD-9 4464
Hospital discharge: ICD-8 4462
Cause of death: ICD-10 M31.3
Cause of death: ICD-9 4464
Cause of death: ICD-8 4462

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_WEGENER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M31
Name in latin Granulomatosis Wegener

Summary Statistics

Key figures

All Female Male
Number of individuals 287 143 144
Unadjusted prevalence (%) 0.11 0.10 0.13
Mean age at first event (years) 52.64 51.52 53.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.98 [0.70, 5.61] 2.0e-1 31
15 years 0.01 1.93 [0.70, 5.37] 2.1e-1 27
5 years 0.00 3.03 [1.14, 8.10] 2.7e-2 12
1 year - - - -

Correlations

Index endpoint: M13_WEGENER – Wegener granulomatosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Wegener granulomatosis
after Wegener granulomatosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Wegener granulomatosis