Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

acute kidney tubular necrosis: Acute renal failure caused by the cell death of the renal tubules. Causes include nephrotoxins, cytotoxic drugs, and antibiotics.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 N14
Cause of death: ICD-10 N14

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector N14_DRUGSANDHEAVYMETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N10-N16
Name in latin Condiciones tubulo-interstitiales et tubulares ex medicamentis et metallis gravibus

Similar endpoints

List of similar endpoints to Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 56 20 36
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 53.23 54.14 52.72

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: N14_DRUGSANDHEAVYMETAL – Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
GWS hits:

Survival analyses between endpoints

Plot

before Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
after Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

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Drugs most likely to be purchased after Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions