Hydronephrosis

hydronephrosis: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 N13.0, N13.1, N13.2, N13.3
Hospital discharge: ICD-9 591
Hospital discharge: ICD-8 591
Cause of death: ICD-10 N13.0, N13.1, N13.2, N13.3
Cause of death: ICD-9 591
Cause of death: ICD-8 591

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector N14_HYDRONEPHR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1761 860 901
Unadjusted prevalence (%) 0.68 0.59 0.80
Mean age at first event (years) 55.72 50.98 60.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.80 [3.99, 8.43] 3.0e-20 408
15 years 0.05 6.81 [4.78, 9.69] 2.1e-26 385
5 years - - - -
1 year - - - -

Correlations

Index endpoint: N14_HYDRONEPHR – Hydronephrosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Hydronephrosis
after Hydronephrosis

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